Dna Replication

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The experimental proof for semiconservative replication of DNA was first shown in a:

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1. **Experiment**: Conducted by Meselson and Stahl in 1958 using heavy nitrogen ($^{15}N$).
2. **Organism**: They used *Escherichia coli* (*E. coli*), which is a common prokaryotic bacterium.
3. **Method**: They cultured the bacteria in medium containing $^{15}NH_4Cl$ and then transferred them to $^{14}N$ medium.
4. **Conclusion**: Centrifugation of DNA confirmed that DNA replication is semi-conservative in bacteria.

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Dna Replication

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