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Fertilization

Mediumbiology

Acrosomal reaction facilitates penetration of which layer surrounding the oocyte?

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About This Question

Subject
biology
Chapter
reproduction
Topic
fertilization
Difficulty
Medium
Year
2025
Tags
FertilizationGametes

Solution

Correct Answer:

Zona pellucida

  1. Acrosome: A cap-like structure on the sperm head filled with enzymes (like hyaluronidase and acrosin).
  2. Mechanism: When sperm makes contact with the ovum, the acrosomal reaction is triggered.
  3. Layers to Penetrate: The sperm must first pass the outer corona radiata, but the acrosomal enzymes specifically facilitate the penetration of the Zona pellucida (the non-cellular glycoprotein layer).
  4. Fusion: Once through the zona pellucida, the sperm membrane fuses with the plasma membrane of the ovum, triggering the block to polyspermy.

This medium difficulty biology question is from the chapter reproduction, covering the topic of fertilization. It appeared in the 2025 exam.

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