Denaturation
Denaturation of proteins involves:
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About This Question
- Subject
- chemistry
- Chapter
- biomolecules
- Topic
- denaturation
- Difficulty
- Easy
- Year
- 2025
Solution
Correct Answer:
Loss of biological activity and 3D structure
Denaturation is the process where a protein loses its native conformation (secondary, tertiary, and quaternary structures) due to external stress like heat, acids, or heavy metal salts.
- The Primary Structure (amino acid sequence and peptide bonds) remains intact.
- Only the weak bonds (H-bonds, hydrophobic interactions) that maintain the 3D shape are broken.
- The protein becomes biologically inactive. A classic example is the coagulation of egg white (albumin) when boiled.
This easy difficulty chemistry question is from the chapter biomolecules, covering the topic of denaturation. It appeared in the 2025 exam.
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