Bioreactors

Question

Sparger in stirred-tank bioreactor primarily provides:

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1. **Bioreactor Design**: Large scale production of biological products requires controlled environments. The stirred-tank bioreactor is most common.
2. **Oxygen Requirement**: Aerobic microorganisms need a constant supply of oxygen for growth.
3. **Aeration System**: The **sparger** is a device (like a perforated pipe) located at the bottom that blows **sterile air bubbles** into the culture medium.
4. **Purpose**: Bubbles increase the surface area for oxygen transfer from the air to the liquid medium, ensuring cells have enough $O_2$ to metabolize.

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Bioreactors

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