Transcription
Mediumbiology
In prokaryotes, promoter consensus -10 region (Pribnow box) is rich in which bases?
Select the correct option:
Solution
Incorrect! Answer:
AT
- Promoter: A DNA sequence where RNA polymerase binds to initiate transcription.
- Pribnow Box: In bacteria (prokaryotes), there is a conserved sequence centered around -10 nucleotides from the start site.
- Sequence: The consensus sequence is TATAAT.
- Base Composition: This region is AT-rich. Because A-T base pairs are held by only two hydrogen bonds (compared to three in G-C), it is energetically easier for the cell to 'melt' the DNA strands here to initiate transcription.
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About This Question
- Subject
- biology
- Chapter
- genetics and evolution
- Topic
- transcription
- Difficulty
- Medium
- Year
- 2025
Solution
Correct Answer:
AT
- Promoter: A DNA sequence where RNA polymerase binds to initiate transcription.
- Pribnow Box: In bacteria (prokaryotes), there is a conserved sequence centered around -10 nucleotides from the start site.
- Sequence: The consensus sequence is TATAAT.
- Base Composition: This region is AT-rich. Because A-T base pairs are held by only two hydrogen bonds (compared to three in G-C), it is energetically easier for the cell to 'melt' the DNA strands here to initiate transcription.
This medium difficulty biology question is from the chapter genetics and evolution, covering the topic of transcription. It appeared in the 2025 exam.
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