Mutation Types

Question

A point mutation replacing one amino acid with another without altering the reading frame is called:

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1. **Point Mutation**: A change in a single nucleotide.
2. **Missense Mutation**: The nucleotide change results in a different codon that codes for a **different amino acid**. This may or may not affect protein function ($e.g.,$ Sickle-cell anemia).
3. **Silent Mutation**: The nucleotide change results in a codon that codes for the **same amino acid** (due to degeneracy/redundancy of the genetic code).
4. **Nonsense Mutation**: The nucleotide change creates a premature **stop codon**, resulting in a truncated, usually non-functional protein.
5. **Frameshift**: Involves insertion or deletion, altering every subsequent codon.

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Mutation Types

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