Golgi Apparatus
Hardbiology
Which Golgi function is essential for lysosome formation?
Select the correct option:
Solution
Incorrect! Answer:
Mannose-6-phosphate tagging
- Golgi Role: The Golgi complex is responsible for the sorting and 'shipping' of proteins received from the ER.
- Lysosomal Enzymes: Enzymes intended for the lysosome (acid hydrolases) must be distinguished from secretory proteins.
- Tagging: In the cis-Golgi, these enzymes are specifically modified with a Mannose-6-phosphate (M6P) tag.
- Sorting: This tag is recognized by M6P receptors in the trans-Golgi network, which packages them into vesicles that eventually become primary lysosomes.
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About This Question
- Subject
- biology
- Chapter
- cell structure and function
- Topic
- golgi apparatus
- Difficulty
- Hard
- Year
- 2025
Solution
Correct Answer:
Mannose-6-phosphate tagging
- Golgi Role: The Golgi complex is responsible for the sorting and 'shipping' of proteins received from the ER.
- Lysosomal Enzymes: Enzymes intended for the lysosome (acid hydrolases) must be distinguished from secretory proteins.
- Tagging: In the cis-Golgi, these enzymes are specifically modified with a Mannose-6-phosphate (M6P) tag.
- Sorting: This tag is recognized by M6P receptors in the trans-Golgi network, which packages them into vesicles that eventually become primary lysosomes.
This hard difficulty biology question is from the chapter cell structure and function, covering the topic of golgi apparatus. It appeared in the 2025 exam.
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