golgi apparatus

Question

Which Golgi function is essential for lysosome formation?

RankGuru · Accepted Answer

1. **Golgi Role**: The Golgi complex is responsible for the sorting and 'shipping' of proteins received from the ER.
2. **Lysosomal Enzymes**: Enzymes intended for the lysosome (acid hydrolases) must be distinguished from secretory proteins.
3. **Tagging**: In the *cis*-Golgi, these enzymes are specifically modified with a **Mannose-6-phosphate ($M6P$)** tag.
4. **Sorting**: This tag is recognized by $M6P$ receptors in the *trans*-Golgi network, which packages them into vesicles that eventually become primary lysosomes.

Rank Guru

golgi apparatus

Select the correct option: