Gene Therapy
Somatic gene therapy aims to:
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About This Question
- Subject
- biology
- Chapter
- biotechnology and its applications
- Topic
- gene therapy
- Difficulty
- Medium
- Year
- 2025
Solution
Correct Answer:
Correct defective genes in body cells
- Objective: Gene therapy is an experimental technique that uses genes to treat or prevent disease.
- Target Cells: Somatic gene therapy involves inserting functional genes into the somatic (body) cells of a patient (e.g., bone marrow cells, lung cells).
- Effect: It corrects the genetic defect only in that individual and the changes are not passed on to offspring.
- Example: Treatment of ADA deficiency by inserting a functional ADA gene into the patient's lymphocytes.
- Germ-line therapy: This would involve changes in sperm or egg cells, which would be heritable (currently restricted in humans).
This medium difficulty biology question is from the chapter biotechnology and its applications, covering the topic of gene therapy. It appeared in the 2025 exam.
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