Digestion: Absorption
Hardbiology
Vitamin B12 absorption in ileum requires which glycoprotein?
Select the correct option:
Solution
Incorrect! Answer:
Intrinsic factor
- Vitamin B12 (Cyanocobalamin): Essential for RBC formation; absorption is complex.
- Stomach Phase: Parietal cells of the stomach secrete a glycoprotein called Intrinsic Factor (IF).
- Binding: Intrinsic factor binds to Vitamin B12 in the small intestine, protecting it from digestion.
- Ileal Phase: The IF−B12 complex is recognized by specific receptors in the terminal ileum (the last part of the small intestine), where absorption occurs.
- Deficiency: Lack of Intrinsic Factor leads to Vitamin B12 deficiency and Pernicious Anemia.
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About This Question
- Subject
- biology
- Chapter
- human physiology
- Topic
- digestion: absorption
- Difficulty
- Hard
- Year
- 2025
Solution
Correct Answer:
Intrinsic factor
- Vitamin B12 (Cyanocobalamin): Essential for RBC formation; absorption is complex.
- Stomach Phase: Parietal cells of the stomach secrete a glycoprotein called Intrinsic Factor (IF).
- Binding: Intrinsic factor binds to Vitamin B12 in the small intestine, protecting it from digestion.
- Ileal Phase: The IF−B12 complex is recognized by specific receptors in the terminal ileum (the last part of the small intestine), where absorption occurs.
- Deficiency: Lack of Intrinsic Factor leads to Vitamin B12 deficiency and Pernicious Anemia.
This hard difficulty biology question is from the chapter human physiology, covering the topic of digestion: absorption. It appeared in the 2025 exam.
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