Blood Coagulation

Question

Which ion is essential for blood coagulation?

RankGuru · Accepted Answer

1. **Coagulation Cascade**: Blood clotting involves a series of complex enzymatic reactions.
2. **Role of Calcium**: **Calcium ions ($Ca^{2+}$)** are required at multiple steps in the cascade, specifically for activating factors and the conversion of prothrombin to thrombin.
3. **Clinical Fact**: Removing calcium from blood (e.g., using EDTA) prevents it from clotting.
4. **Conclusion**: $Ca^{2+}$ is the essential ion.

Blood Coagulation

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